Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Depth dose and profile analysis using Library Least-Squares method.

L Wielopolski1, I J Zedek, A G Meek

  • 1Department of Radiation Oncology, University Hospital, Stony Brook, NY 11794-7028.

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of ruthenium on DNA by XRF.

Biological trace element research·2013
Same author

Description of an XRF system for multielemental analysis.

Biological trace element research·2013
Same author

Nuclear spectroscopy for in situ soil elemental analysis: Monte Carlo simulations.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2012
Same author

Measuring partial body potassium in the legs of patients with spinal cord injury: a new approach.

Journal of applied physiology (Bethesda, Md. : 1985)·2008
Same author

Proof-of-Principle to Measure Potassium in the Human Brain: A Feasibility Study.

International journal of body composition research·2007
Same author

Measuring partial body potassium in the arm versus total body potassium.

Journal of applied physiology (Bethesda, Md. : 1985)·2006
Same journal

A case study of inhale and exhale split-course VMAT treatment to minimize dose to ribs.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Prospective clinical implementation of the robust optimization planning technique in long-course photon radiotherapy treatment for lung cancer.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Dosimetric comparison of target coverage, dose gradient, and low-dose bath in left-sided accelerated partial breast irradiation: CyberKnife versus conventional linac-based noncoplanar VMAT and 3D-CRT.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Cross-prescription validation of knowledge-based planning in prostate VMAT using a structured validation framework.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Dosimetric evaluation of beam block techniques in helical tomotherapy for extranodal nasal-type NK/T-cell lymphoma.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

The dosimetric impact to bladder utilizing the Varian Edge linear accelerator for prostate stereotactic body radiation therapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
See all related articles

The Library Least-Squares method effectively detects subtle changes in medical linear accelerator electron and photon beams. This technique offers quantitative monitoring of treatment beam characteristics, crucial for radiation therapy accuracy.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Beam Metrology

Background:

  • Accurate dosimetry and beam characterization are critical for effective radiation therapy.
  • Medical linear accelerators (LINACs) deliver electron and photon beams for cancer treatment.
  • Monitoring beam stability ensures consistent and safe patient treatments.

Purpose of the Study:

  • To evaluate the Library Least-Squares (LLS) method for detecting alterations in LINAC beam characteristics.
  • To assess the sensitivity of the LLS method to small changes in electron and photon beam parameters.
  • To demonstrate the quantitative monitoring capabilities of the LLS method for clinical beams.

Main Methods:

  • Application of the Library Least-Squares (LLS) method.
  • Analysis of depth dose and beam profiles for 6 and 20 MeV electron beams.

Related Experiment Videos

  • Analysis of 6 MeV photon beams from medical linear accelerators.
  • Introduction of controlled perturbations (e.g., aluminum absorber, gantry/collimator rotation).

    • Main Results:

    • The LLS method clearly identified beam energy changes of 0.78% and 0.32% in low and high energy electron beams, respectively, induced by a 0.1 mm aluminum absorber.
    • Changes in the photon beam characteristics due to gantry or collimator rotation were detectable.
    • Residual distributions effectively visualized the impact of introduced perturbations.

    Conclusions:

    • The Library Least-Squares method is a viable tool for detecting and quantifying changes in medical linear accelerator beams.
    • The LLS method demonstrates high sensitivity to minor variations in beam energy and profile.
    • This technique supports quantitative monitoring of treatment beam characteristics, enhancing radiation therapy quality assurance.