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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

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Related Experiment Video

Updated: Jun 27, 2026

Long-Term Mouse Spinal Cord Organotypic Slice Culture as a Platform for Validating Cell Transplantation in Spinal Cord Injury
07:37

Long-Term Mouse Spinal Cord Organotypic Slice Culture as a Platform for Validating Cell Transplantation in Spinal Cord Injury

Published on: April 12, 2024

Stem cell spinal cord regeneration: first do no harm.

M Legge1, L M Jones

  • 1Department of Biochemistry and Pathology, University of Otago, Dunedin, New Zealand. mike.legge@stonebow.otago.ac.nz

Journal of Medical Ethics
|December 2, 2008
PubMed
Summary
This summary is machine-generated.

Stem cell therapy offers hope for curing spinal cord injury. This research explores the physiological effects and ethical considerations of successful in vivo spinal cord repair.

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Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury
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Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury

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Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury
09:56

Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury

Published on: July 27, 2014

Related Experiment Videos

Last Updated: Jun 27, 2026

Long-Term Mouse Spinal Cord Organotypic Slice Culture as a Platform for Validating Cell Transplantation in Spinal Cord Injury
07:37

Long-Term Mouse Spinal Cord Organotypic Slice Culture as a Platform for Validating Cell Transplantation in Spinal Cord Injury

Published on: April 12, 2024

Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury
10:56

Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury

Published on: December 17, 2014

Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury
09:56

Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury

Published on: July 27, 2014

Area of Science:

  • Regenerative Medicine
  • Neuroscience
  • Bioethics

Background:

  • Spinal cord injury (SCI) presents significant challenges in neurological recovery.
  • Stem cell therapy is a promising avenue for SCI treatment.
  • Current research focuses on the potential for "curing" SCI.

Purpose of the Study:

  • To examine the physiological implications of successful in vivo spinal cord repair.
  • To address the ethical issues associated with revolutionary stem cell therapies for SCI.

Main Methods:

  • This communication is a theoretical review and discussion.
  • It synthesizes existing knowledge on stem cell therapy and SCI.
  • It analyzes potential outcomes and ethical frameworks.

Main Results:

  • Successful in vivo spinal cord repair via stem cells could lead to profound physiological changes.
  • The advancement of this therapy necessitates careful consideration of ethical dilemmas.
  • Potential benefits must be weighed against societal and individual ethical concerns.

Conclusions:

  • Stem cell therapy holds revolutionary potential for spinal cord injury.
  • Addressing both physiological and ethical dimensions is crucial for responsible advancement.
  • Further dialogue is needed to navigate the complexities of this emerging field.