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Updated: Jun 27, 2026

A Swine Model of Neonatal Asphyxia
Published on: October 11, 2011
[Comparison of oxygen saturation among newborns with bronchopulmonary dysplasia during and after feeding]
Carlos Antonio Tapia-Rombo1, Gabriela Munguía-Medina, Víctor Joel Saucedo-Zavala
1Servicio de Neonatología, Unidad Médica de Alta Especialidad, Hospital General, Centro Médico Nacional La Raza, IMSS, México D.F., México. tapiachar@yahoo.com.mx
Insights
Infants with bronchopulmonary dysplasia (BPD) experience significant oxygen drops during feeding. Supplemental oxygen is crucial to maintain adequate peripheral oxygen saturation (SpO2) above 88% in these vulnerable infants.
Area of Science:
- Neonatal Medicine
- Pediatric Pulmonology
- Critical Care
Background:
- Bronchopulmonary dysplasia (BPD) frequently causes hypoxemia, particularly during infant feeding.
- Monitoring oxygenation is critical for managing BPD complications.
Purpose of the Study:
- To assess peripheral oxygen saturation (SpO2) in infants diagnosed with BPD.
- To analyze SpO2 trends before, during, and after feeding sessions.
Main Methods:
- Prospective study of BPD patients from July to September 2005.
- Peripheral oxygen saturation (SpO2) measured five times per feeding event using digital pulsioxymetry.
- Statistical analysis with alpha levels set at p<0.05.
Main Results:
- 18 BPD patients and 67 feeding events were analyzed, totaling 335 SpO2 recordings.
- 16 out of 18 patients experienced frequent desaturation events (SpO2 < 88%) during feeding.
- 67% of participants (n=12) showed SpO2 levels dropping to 80% during recordings (p<0.001).
Conclusions:
- Feeding significantly decreases SpO2 in BPD infants, with severe desaturations (SpO2 < 80%) occurring in two-thirds of cases.
- Increased oxygen concentration during feeding is recommended to maintain SpO2 levels at or above 88%.
Background:
Bronchopulmonary dysplasia (BPD) is associated with frequent events of hypoxemia specially during feeding.
Objective:
Determine peripheral oxygen saturation (SpO2) among infants with BPD before, during and after feeding.
Methods:
Patients with diagnosis of BPD were prospectively studied between July-September, 2005. SpO2 was measured with a manual digital pulsioxymeter 5 times during feeding. Alpha levels were set at p<0.05.
Results:
67 events were studied in 18 patients. For each participant, oxygen saturation was measured five times yielding a total of 335 recordings. Frequent desaturation episodes were recorded during feeding, (SpO2<88%) in 16 of the 18 cases. SpO2 reached 80% for some recordings among 67% of participants (n=12), with p<0.001.
Conclusion:
Among BDP patients, SpO2 decreases during feeding, reaching severe desaturations (SpO2<80%) among in two thirds of the cases. Oxygen concentration must be sufficiently increased during feeding in order to rise the level of SpO2 to a minimum of 88%.
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