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Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

Cardiomyopathy I: Introduction and Classification

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Myocarditis II: Clinical Features and Diagnostic Tests

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Related Experiment Video

Updated: Jun 27, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

Cardiac sarcoidosis: a case report.

José Roberto Silva¹, Emanuel Correia, Pedro Gama

¹Serviço Cardiologia, Hospital São Teotónio, EPE, Viseu, Portugal. robertjomd@gmail.com

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology

|December 3, 2008

Summary

Cardiac sarcoidosis affects about 5% of sarcoidosis patients, causing varied heart issues from arrhythmias to sudden death. Diagnosis is challenging due to the disease

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Last Updated: Jun 27, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

Area of Science:

Cardiology
Immunology
Pathology

Background:

Sarcoidosis is a multisystem inflammatory disease.
Cardiac involvement occurs in ~5% of sarcoidosis patients.
Cardiac sarcoidosis presents a diagnostic challenge.

Observation:

Disease course is highly variable, from arrhythmias to heart block and sudden death.
Endomyocardial biopsy has low diagnostic yield due to patchy granuloma distribution.
Clinical suspicion is key in patients with known sarcoidosis and new cardiac symptoms.

Findings:

Cardiac sarcoidosis can manifest as arrhythmias, conduction abnormalities, heart failure, or ECG changes.
Diagnosis relies on clinical suspicion and exclusion of other causes.
Case report and review highlight diagnostic difficulties and management considerations.

Implications:

Early recognition and diagnosis of cardiac sarcoidosis are crucial for patient outcomes.
Further research into improved diagnostic methods for cardiac sarcoidosis is warranted.
Multidisciplinary approaches may improve management of this rare condition.