Related Experiment Video
Updated: Jun 27, 2026

Cell-Free DNA Integrity Analysis in Urine Samples
Published on: January 5, 2017
[Usefulness of urine cytology for bladder carcinoma diagnosis: comparative study with biopsy]
Ma Garcia Castro1, E Fernández Fernández, M C Martín Corriente
1Sección de Citología Clínica,. Hospital Universitario de Canarias, La Laguna, Tenerife. candelarigc@yahoo.es
Objectives:
Traditionally, urine cytology has been considered as the gold standard for bladder cancer screening. However, new methods are playing new roles in these cases. In order to assess the value of cytology of voided urine we performed one comparative study between cytology and biopsy.
Methods:
We retrospectively analyzed the results of urine cytology and biopsy follow-up in 109 patients. All cytologies were from voided urine. They were cytocentrifuged and stained with Papanicolaou stain.
Results:
We found 70 true positive cases and 24 true negative cases. Sensitivity was calculated to be 97% and specifity 96-100%. 12 cases had the first cystoscopy test and biopsy negative, as the cancer was diagnosed in the second biopsy.
Conclusions:
Patients with clearly positive urine cytology, which was not confirmed in a first cystoscopic study, should be carefully followed up to identify a possible bladder or upper urinary tract cancer. The urine cytology still has a significant role as the gold standard for bladder cancer screening.
More Related Videos
05:33Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
06:12Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model
Published on: May 29, 2015
Related Concept Videos
Urine Studies II: Urine Culture and Sensitivity Test
Imaging Studies VI: Voiding Cystourethrography and Cystography
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Urine Studies I: Urinalysis
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urologic Endoscopic Procedure: Cystoscopic Examination