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DNA damage-inducible loci in Salmonella typhimurium
1Department of Cancer Biology, Harvard University School of Public Health, Boston, Massachusetts 02115.
Journal of Bacteriology
|June 1, 1991
Abstract:
lac operon fusions to DNA damage-inducible (din) loci were generated in Salmonella typhimurium LT2. Many of these din fusions were efficiently repressed by cloned Escherichia coli LexA, while others were not; all required RecA for induction. Several din fusions exhibited strong inducibility and will be useful in developing an SOS induction assay in S. typhimurium to detect genotoxins.