Assessing the validity of modulation transfer function evaluation techniques with application to small area and
B D Price1, C J Esbrand, A Olivo
1Department of Medical Physics and Bioengineering, University College London, London, United Kingdom. bprice@medphys.ucl.ac.uk
The Review of Scientific Instruments
|December 3, 2008
Summary
A new intelligent imaging system (I-Imas) uses a step and shoot x-ray technique to optimize dose distribution. This method slightly reduces overall spatial resolution by 0.1 lp/mm compared to individual image resolution.
Area of Science:
- Medical Imaging Physics
- Radiological Technology
- Image Analysis
Background:
- A novel prototype step and shoot x-ray system, the intelligent imaging system (I-Imas), has been developed.
- This system modulates x-ray beam intensity based on identified regions of interest to optimize dose distribution.
- Such systems offer potential for improved diagnostic capability at equivalent patient dose levels.
Purpose of the Study:
- To investigate the impact of the step and shoot acquisition modality on the overall spatial resolution of the I-Imas.
- To evaluate the accuracy of Modulation Transfer Function (MTF) determination for varying sensor sizes.
- To compare the MTF of large composite images with that of individual constituent images.
Main Methods:
- Review and selection of optimal Modulation Transfer Function (MTF) evaluation techniques.
- Investigation of MTF accuracy for different sensor areas.
- Analysis of spatial resolution differences between composite and individual images acquired using the step and shoot method.
Main Results:
- For a fixed pixel pitch, MTF determination accuracy slightly decreases with smaller sensor areas, causing perceived resolution variations up to 0.1 lp/mm.
- The step and shoot acquisition technique results in a minor overall degradation of spatial resolution.
- The spatial resolution of composite images was found to be 0.1 lp/mm lower than that of individual images.
Conclusions:
- The intelligent imaging system (I-Imas) demonstrates a slight reduction in spatial resolution due to its step and shoot acquisition method.
- Accurate MTF determination is marginally affected by sensor size in this system.
- The findings are crucial as step and shoot systems become more prevalent in medical imaging.


