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Updated: Jun 27, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Epibulbar melanoma in a foal
Richard J McMullen1, Alison B Clode, Arun Kumar R Pandiri
1Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
A rare epibulbar melanoma was diagnosed in a foal. This equine eye tumor showed invasion into the choroid but had no recurrence 14 months post-surgery.
Area of Science:
- Veterinary Ophthalmology
- Equine Pathology
- Ophthalmology
Background:
- Epibulbar melanomas are rare in foals.
- Early diagnosis and treatment are crucial for ocular tumors.
Observation:
- A 6-month-old foal presented with an epibulbar mass, initially suspected as staphyloma or congenital anomaly.
- Surgical excision was attempted but the tumor's infiltrative nature required enucleation.
- Histopathology confirmed a heavily pigmented, infiltrative melanocytic neoplasm with choroidal invasion.
Findings:
- The epibulbar melanoma exhibited characteristics of a low-grade malignant neoplasm.
- Infiltration into the cornea, sclera, and choroid was confirmed histopathologically.
- Despite invasion, no recurrence was observed 14 months after initial surgical debulking and subsequent enucleation.
Implications:
- This case highlights the importance of considering melanoma in equine ocular masses.
- Understanding the infiltrative potential of epibulbar melanomas is critical for surgical planning.
- Further research into equine ocular tumor biology may improve diagnostic and therapeutic strategies.
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