Related Experiment Video
Updated: Jun 27, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Postoperative management of pigmented villonodular synovitis in a single subject
Eric J Hegedus1, Kristen Theresa
1Duke University School of Medicine, Department of Community and Family Medicine, Durham, NC 27705, USA. eric.hegedus@duke.edu
Study Design:
Case report.
Background:
Pigmented villonodular synovitis (PVNS) is a rare, benign disorder characterized by idiopathic proliferation affecting the synovium of joints, tendon sheaths, and bursae. Diagnosing PVNS in the knee is difficult because the clinical presentation and symptoms mimic those of more common disorders at the joint, such as internal derangements or arthritis. Operative treatment of PVNS typically consists of arthroscopic or open synovectomy, but no reports of postoperative rehabilitation exist.
Case Description:
This case describes the postoperative rehabilitation of a 46-year-old female who had left knee surgery secondary to PVNS. Rehabilitation consisted of combined manual therapy, exercise, and gait training to improve function and gait, and cognitive-behavioral techniques to improve self-efficacy.
Outcomes:
All impairments improved in 2.5 months of physical therapy to normal, and the patient estimated 80% to 90% return to function.
Discussion:
This patient obtained excellent outcomes in 2.5 months of physical therapy following surgery for PVNS. Although no firm conclusions can be drawn from a case report, this patient responded well to a biopsychosocial approach that combined physical therapy with cognitive-behavioral techniques.
Level Of Evidence:
Therapy, level 4.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD: