Related Experiment Video
Updated: Jun 27, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Coronary artery bypass grafting in patients on maintenance dialysis: is peritoneal dialysis a risk factor of
Hui Zhong1, Tirone David, Ai Hua Zhang
1Department of Medicine, Division of Nephrology, University Health Network and University of Toronto, Toronto, ON, Canada. zhongyihui@hotmail.com
Insights
Older age and peritoneal dialysis increase operative mortality risk in patients undergoing coronary artery bypass grafting (CABG). Extra caution is advised for elderly peritoneal dialysis patients considering CABG surgery.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Critical Care Medicine
Background:
- Coronary artery bypass grafting (CABG) is increasingly performed in patients on dialysis.
- Identifying operative mortality risk factors in this population is crucial.
Purpose of the Study:
- To identify risk factors for operative mortality in dialysis patients undergoing CABG.
Main Methods:
- Retrospective analysis of 105 dialysis patients (maintenance dialysis for ≥2 months) who underwent CABG.
- Data collected included comorbidities, procedures, and outcomes.
- Logistic regression analysis was used to determine risk factors for operative mortality.
Main Results:
- Overall in-hospital mortality was 7.6%.
- Older age (≥70 years) and peritoneal dialysis (PD) were identified as independent risk factors for operative mortality.
- PD patients experienced higher rates of post-operative complications like dialysate leak and peritonitis.
Conclusions:
- Older patients on peritoneal dialysis (PD) face higher operative mortality following CABG compared to hemodialysis (HD) patients.
- Careful consideration and potentially enhanced monitoring are recommended for elderly PD patients undergoing CABG.
- Further research is needed to elucidate the specific reasons for increased mortality in this subgroup.
Background:
Increasing numbers of patients on dialysis are undergoing coronary artery bypass grafting (CABG). We undertook this retrospective study to identify risk factors of operative mortality in dialysis patients who underwent CABG.
Patients And Methods:
We performed retrospective analysis of 105 patients who were on dialysis for at least two months before surgery and who underwent CABG in Toronto General Hospital from 1997 to 2006. Using prospectively collected data from the Division of Cardiovascular Surgery Database of Toronto General Hospital, we collected data on comorbidities, procedures, modality change during hospitalization, and operative outcomes. Logistic regression was used to assess risk factors of operative mortality.
Results:
One hundred and five maintenance dialysis patients (40 PD and 65 HD) who met the inclusion criteria were studied. Overall in-hospital mortality was 7.6%. Atrial fibrillation and pneumonia occurred in 16.2 and 9.5%, respectively, of all dialysis patients. Among PD patients, rates of post-operative dialysate leak and peritonitis were 10 and 12.5%, respectively. Among HD patients, 4.6% experienced post-operative AV access thrombosis. Logistic regression showed older age (>or=70 years) and peritoneal dialysis are independent risk factors of operative mortality.
Conclusion:
In this retrospective study, older patients on PD had higher operative mortality than HD patients. These findings suggest extra care should be taken when CABG is considered for PD patients over 70 years old. In this study we could not identify the reason(s) for the high mortality of elderly peritoneal dialysis patients undergoing CABG.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Hemodialysis II: Procedure and Complications
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis
Peritoneal Dialysis III: Nursing Management
