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Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry

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Quantifying the relation between bond number and myoblast proliferation.

Tanyarut Boontheekul¹, Hyun-Joon Kong, Susan X Hsiong

¹Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

Faraday Discussions

|December 4, 2008

Summary

Cell proliferation depends on how peptide fragments like arginine-glycine-aspartic acid (RGD) are presented. Increased RGD density and affinity enhance cell growth, while nanoscale distribution has a complex effect, impacting cell adhesion and biomaterial design.

Area of Science:

Biomaterials Science
Cell Biology
Biophysics

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