Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Polymers

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

Polymers

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

Polymers

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

Polytene Chromosomes

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...

Intralumenal Vesicles and Multivesicular Bodies

Intralumenal Vesicles and Multivesicular Bodies

Intraluminal vesicles (ILVs) are small vesicles 50-80 nm in diameter formed during the maturation of early endosomes. A specialized endosome containing numerous ILVs is called a multivesicular body (MVB). ILVs contain internalized molecules such as antigens, nucleic acids, proteins, and metabolites. Some of these molecules are released from the MVBs inside exosomes and are transported to other cells. Other MVBs contain molecules that are retained in the ILVs and are later degraded within the...

COP Coated Vesicles

COP Coated Vesicles

Membrane-enclosed structures called vesicles transport proteins and lipids across the cell. The vesicles derive their cargo from the plasma membrane, Golgi, ER, or endosome. Coated vesicles are spherical, protein-coated carriers with a 50–100 nm diameter that mediate bidirectional transport between the ER and the Golgi. The distribution of proteins between the ER and Golgi complex is dynamic and is maintained by different coated vesicles. Their formation is driven by the assembly of different...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Enhancing Combat Surgical Readiness: The Development and Impact of the Combat Craniomaxillofacial Trauma Surgery Course.

Military medicine·2026

Same author

Recombinant Protein Nanoparticles for Dual-Stage Inhibition of SARS-CoV‑2 Infection.

ACS nanoscience Au·2026

Same author

Correction to "Critical Micelle Concentration of Multiblock Copolymers in Immiscible Homopolymer Blends".

ACS macro letters·2026

Same author

Critical Micelle Concentration of Multiblock Copolymers in Immiscible Homopolymer Blends.

ACS macro letters·2026

Same author

Measuring the traction forces of upstream-migrating hematopoietic-like KG1a cells under shear flow.

Biophysical journal·2025

Same author

Interfacial Failure in Graft Block Copolymer-Reinforced Polymer Blends.

ACS macro letters·2025

Same journal

Ambient stability and surface adhesion of 2D polyaramid nanofilms.

Faraday discussions·2026

Same journal

Spiers Memorial Lecture: Spin-mediated promotion of magnetic metal catalysts.

Faraday discussions·2026

Same journal

Helium spin-echo as a surface-sensitive probe of vibrational energy dissipation.

Faraday discussions·2026

Same journal

Near-infrared vibrational second harmonic generation: a new nonlinear interfacial vibrational spectroscopy.

Faraday discussions·2026

Same journal

CO on a Rh/Fe<sub>3</sub>O<sub>4</sub> single-atom catalyst: high-resolution infrared spectroscopy and near-ambient-pressure scanning tunnelling microscopy.

Faraday discussions·2026

Same journal

Evolution of size-selected Pt cluster catalysts on prototypical oxide supports.

Faraday discussions·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Published on: May 26, 2016

Leuko-polymersomes.

Daniel A Hammer¹, Gregory P Robbins, Jered B Haun

¹School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA. hammer@seas.upenn.edu

Faraday Discussions

|December 4, 2008

Summary

This summary is machine-generated.

Researchers created artificial cells called polymersomes that mimic white blood cell adhesion. These "leuko-polymersomes" can be used to target diseases like inflammation, cancer, and cardiovascular conditions.

More Related Videos

Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation

Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation

Published on: August 11, 2018

Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure

Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure

Published on: April 21, 2021

Related Experiment Videos

Last Updated: Jun 27, 2026

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Published on: May 26, 2016

Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation

Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation

Published on: August 11, 2018

Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure

Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure

Published on: April 21, 2021

Area of Science:

Biomaterials Science
Cellular Biology
Nanotechnology

Background:

Polymersomes are self-assembled vesicles from block co-polymers with tunable properties.
Their versatility allows for applications in drug delivery and materials science.
Leukocyte adhesion is crucial for immune response and disease progression.

Purpose of the Study:

To engineer polymersomes with leukocyte-like adhesive properties.
To mimic leukocyte adhesion pathways using synthetic vesicles.
To explore potential applications in disease monitoring and treatment.

Main Methods:

Functionalizing polymersome surfaces with biotin.
Utilizing avidin-biotin chemistry to attach selectin and integrin ligands.
Testing particle adhesion under physiological flow conditions.

Main Results:

Successfully created polymersomes with specific adhesive capabilities.
Demonstrated adhesion mimicking leukocyte behavior in blood flow.
Confirmed specificity of the adhesion mechanism.

Conclusions:

Leuko-polymersomes effectively replicate leukocyte adhesion dynamics.
This technology offers a novel platform for targeting inflammatory, cancerous, and cardiovascular diseases.
Further development could lead to advanced diagnostic and therapeutic tools.