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Updated: Jun 27, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Thrombolysis in recurrent lacunar stroke: a case example
1Department of Neurology, People Hospital, Vietnam. dr_nguyenhuythang@yahoo.com
European Journal of Neurology
|December 4, 2008
Summary
Intravenous thrombolysis may be safe for early recurrent lacunar stroke. This treatment led to significant improvement in a patient who experienced a second stroke within a week of the first.
Area of Science:
- Neurology
- Vascular Neurology
- Emergency Medicine
Background:
- Early recurrent stroke presents a significant clinical challenge.
- Lacunar infarcts, though often small, can lead to severe disability.
- Timely intervention is crucial for improving outcomes in recurrent stroke.
Observation:
- A 62-year-old male experienced a lacunar infarct in the left putamen with near-complete recovery.
- Seven days post-initial stroke, the patient suffered a recurrent ischemic event (left internal capsule infarct).
- Symptoms of recurrent stroke appeared rapidly, necessitating urgent treatment.
Findings:
- Intravenous thrombolysis with alteplase (0.9 mg/kg) was administered 40 minutes after symptom onset of the recurrent stroke.
- The patient demonstrated significant neurological improvement following thrombolytic therapy.
- This case suggests a potential benefit of thrombolysis in specific recurrent stroke scenarios.
Implications:
- Intravenous thrombolysis could be a viable option for early recurrent lacunar stroke.
- Patient selection, considering hemorrhage risk, is critical for safe thrombolysis in recurrent stroke.
- Further research is warranted to establish the safety and efficacy of thrombolysis for early recurrent ischemic events.
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