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Updated: Jun 27, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[Anxiety and depression in patients with medical diseases]
Gerhard Schüssler1, Gereon Heuft
1Universitätsklinik für Medizinische Psychologie und Psychotherapie, Medizinische Universität Innsbruck. medpsych@uki.at
Objectives:
Anxiety and depression are more prevalent in patients with medical diseases than in the general population. The current diagnostic systems for depression/anxiety in the field of comorbidity, however, are problematic.
Results And Conclusions:
Higher comorbidity has deteriorating consequences in all bio-psycho-social respects. The aetiologic connections between medical disease and psychological disorders are complex bidirectional somato-psycho-somatic ones. Seven modalities of comorbidity for coronary heart disease (myocardial infarction) and depression/anxiety are discussed. The psychopharmacological and psychotherapeutic treatment of anxiety/depression in patients with medical diseases follows general guidelines.
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