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Intrabronchial foreign body extracted with tranilast and corticosteroid
Yasuji Terada1, Yasuto Sakaguchi, Tomoya Kono
1Department of Thoracic Surgery, Nagahama City Hospital, Nagahama, Japan. yaterada@ex.biwa.ne.jp
Abstract:
We present a case of intrabronchial foreign body buried in granulation tissue, which was successfully extracted administrating tranilast (n-[3,4-dimethoxycinnamoyl] anthranilic acid), suppressing collagen synthesis by fibroblasts in keloid and hypertrophic scars, and corticosteroid. Bronchoscopy of a 74-year-old man showed the nail was buried in reactive granulation tissue and could not be observed from the surface. Tranilast at 300 mg/day and methylprednisolone at 250 mg/day were prescribed for 4 days, followed by a reduction of the corticosteroid to 40 mg/day for 3 days. Seven days later, the granulation tissue and mucosal edema were diminished, and the nail was successfully extracted.
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