Association between carotid and coronary artery disease in patients with aortic valve stenosis: an angiographic study

Francesco Antonini-Canterin1, Elisa Leiballi, Michele Capanna

  • 1Cardiologia, ARC, Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy. cardiologia@aopn.fvg.it

Angiology
|December 4, 2008
PubMed

Insights

Patients with aortic stenosis and carotid artery disease have a high likelihood of also having coronary artery disease. Carotid artery disease is a strong predictor of coronary artery disease in these patients.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Aortic stenosis frequently coexists with coronary artery disease.
  • Limited data exists on the association between coronary artery disease and carotid artery disease in patients with aortic stenosis.

Purpose of the Study:

  • To investigate the relationship between carotid artery disease and coronary artery disease in patients undergoing aortic valve replacement.

Main Methods:

  • 317 patients with aortic stenosis underwent simultaneous carotid and coronary angiography.
  • Univariate and multivariate analyses were performed to identify predictors of coronary artery disease.

Main Results:

  • Carotid artery disease, angina, and age were independent predictors of coronary artery disease.
  • The combination of carotid artery disease and angina identified groups with varying coronary artery disease prevalence, from 21% to 85%.

Conclusions:

  • Significant carotid artery disease is a robust marker for significant coronary artery disease in patients with symptomatic aortic stenosis.
  • Identifying carotid artery disease can aid in risk stratification for coronary artery disease in this population.
Abstract

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