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Updated: Jun 27, 2026

A Protocol to Acquire the Degenerative Tenocyte from Humans
Published on: June 9, 2018
A new integrative model of lateral epicondylalgia
B K Coombes1, L Bisset, B Vicenzino
1Division of Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Queensland, Australia.
Abstract:
Tennis elbow or lateral epicondylalgia is a diagnosis familiar to many within the general community and presents with an uncomplicated clinical picture in most cases. However, the underlying pathophysiology presents a more complex state and its management has not been conclusively determined. Research on this topic extends across anatomical, biomechanical and clinical literature; however, integration of findings is lacking. We propose that the current understanding of the underlying pathophysiology of lateral epicondylalgia can be conceptualised as encompassing three interrelated components: (i) the local tendon pathology, (ii) changes in the pain system, and (iii) motor system impairments. This paper presents a model that integrates these components on the basis of a literature review with the express aim of assisting in the targeting of specific treatments or combinations thereof to individual patients.

