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Related Experiment Video

Updated: Jun 27, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

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Radiation reduction with prospective ECG-triggering acquisition using 64-multidetector Computed Tomographic

Ambarish Gopal¹, Song S Mao, Daniel Karlsberg

¹Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA, 90502, USA.

The International Journal of Cardiovascular Imaging

|December 4, 2008

Summary

Prospective ECG-triggered computed tomographic angiography (CTA) with 100 kVp significantly reduces radiation dose by up to 90%. This advanced imaging technique maintains diagnostic image quality, offering a safer alternative for patients undergoing CTA scans.

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Area of Science:

Radiology and Imaging
Medical Physics
Cardiovascular Imaging

Background:

Current 64-multidetector Computed Tomographic scanners (MDCT) often use retrospective overlapping helical acquisition (RS-OHA), leading to higher radiation doses.
While dose modulation and field-of-view limitation reduce radiation in computed tomographic angiography (CTA), further dose reduction without compromising image quality is highly desirable.

Purpose of the Study:

To compare effective radiation dose and image quality between different dose-reduction techniques for CTA using 64-MDCT scanners.
Evaluate the efficacy of prospective ECG-triggering acquisition versus retrospective triggering.

Main Methods:

149 patients underwent CT coronary angiography using 64-MDCT with three algorithms: retrospective triggering with dose modulation, prospective triggering with padding, and prospective triggering without padding.
Radiation doses and signal-to-noise ratio (SNR) of the ascending aorta were measured and compared.
Utilized 100 kVp or 120 kVp based on patient body habitus.

Main Results:

Prospective imaging reduced radiation exposure by 82.6% compared to retrospective imaging (P < 0.001).
Using prospective imaging with 100 kVp and no padding reduced radiation dose by 90% (P < 0.001).
Image quality, assessed by SNR, remained diagnostic across all evaluated prospective ECG-triggered acquisition protocols at 100 kVp.

Conclusions:

Prospective ECG-triggered acquisition, particularly with 100 kVp and single-phase data acquisition, significantly lowers radiation dose in CTA.
This method achieves substantial radiation reduction (up to 90%) while preserving diagnostic image quality.
Prospective triggering represents a valuable advancement for reducing radiation burden in CTA examinations.