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Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...

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Related Experiment Video

Updated: Jun 27, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

A brief computerized self-screen for dementia.

Benzi M Kluger1, Lauren V Saunders, Wei Hou

  • 1University of Florida, Gainesville, FL 32610, USA.

Journal of Clinical and Experimental Neuropsychology
|December 4, 2008
PubMed
Summary
This summary is machine-generated.

A new computerized dementia screening test is user-friendly for elderly individuals. It shows comparable validity to the MMSE and correlates with traditional neuropsychological tests.

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

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Published on: January 11, 2020

Area of Science:

  • Neuropsychology
  • Public Health
  • Geriatrics

Background:

  • Arthur Benton highlighted the public health importance of neuropsychological tests for dementia screening.
  • Growing dementia prevalence necessitates validated screening tools for early detection and intervention.
  • Improving treatments for dementia underscore the need for accessible and accurate diagnostic methods.

Purpose of the Study:

  • To introduce a novel, brief, self-administered computerized screening test for dementia.
  • To evaluate the user-friendliness of the computerized test for elderly individuals, including those with dementia.
  • To assess the discriminant validity and correlation with established tests.

Main Methods:

  • Development of a user-friendly, self-administered computerized screening test for dementia.
  • Comparison of the test's discriminant validity against the Mini Mental State Examination (MMSE).
  • Correlation analysis of the test's subscales with traditional neuropsychological assessments.

Main Results:

  • The computerized dementia screening test is user-friendly for most elderly participants, including those with dementia.
  • The test demonstrated discriminant validity comparable to the MMSE.
  • Subscales of the new test showed good correlation with established neuropsychological tests.

Conclusions:

  • The developed computerized test offers a promising, accessible tool for dementia screening in the elderly population.
  • Its comparable validity to the MMSE and correlation with traditional tests support its clinical utility.
  • Further research should explore its broader applications and long-term impact on dementia care.