Related Experiment Video
Updated: Jun 27, 2026

08:38
Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food
Published on: May 6, 2013
Summary
Undiagnosed diabetes affects up to 500,000 in England. Many diagnosed cases are miscoded, and maternal diabetes increases stillbirth risk fivefold, highlighting significant public health challenges.
Area of Science:
- Public Health
- Endocrinology
- Epidemiology
Background:
- An estimated 500,000 individuals in England may have undiagnosed diabetes.
- A significant proportion of diagnosed diabetes cases (up to 50%) might be improperly coded within the payment by results system.
- Maternal diabetes is associated with a five-fold increase in stillbirth rates compared to the general population.
Purpose of the Study:
- To estimate the prevalence of undiagnosed diabetes in England.
- To assess the accuracy of diabetes coding within the payment by results framework.
- To quantify the impact of maternal diabetes on stillbirth rates.
Main Methods:
- Utilizing national health data and statistical modeling to estimate undiagnosed diabetes prevalence.
- Analyzing electronic health records and administrative data to evaluate coding accuracy.
- Conducting a retrospective cohort study comparing stillbirth rates in pregnancies with and without maternal diabetes.
Main Results:
- Up to 500,000 people in England may have undiagnosed diabetes.
- As many as 50% of individuals with diabetes may have incorrect coding under payment by results.
- Children born to mothers with diabetes exhibit a five times higher stillbirth rate than the average.
Conclusions:
- Significant gaps exist in diabetes diagnosis and management in England.
- Inaccurate coding practices may impact healthcare resource allocation and quality assessment.
- Maternal diabetes poses a substantial risk to fetal outcomes, necessitating targeted interventions.
Related Concept Videos
Bulimia Nervosa
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Sources of Food Contamination
Contamination of food by microbial agents and natural toxins poses significant risks to public health. These hazards can be introduced at various points across the food supply chain, ranging from environmental sources to processing and storage stages. Understanding these contamination pathways is critical for developing strategies to ensure food safety.Seafood is particularly vulnerable to contamination through both environmental exposure and microbial colonization. Toxins from harmful algal...
Phagocytosis
Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis (“cellular eating”) is one of three major types of endocytosis. Cells use phagocytosis to take in large objects—such as other cells (or their debris), bacteria, and even viruses.The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). It is perhaps unsurprising, that many...
Phagocytosis
Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis ("cellular eating") is one of three major types of endocytosis. Cells use phagocytosis to take in large objects, such as other cells (or their debris), bacteria, and even viruses.
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells, including...
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells, including...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

