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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
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Published on: February 24, 2023

Melioidosis.

P Krishnan1, Sushmitha Fernandes, Jayanthi Savio

  • 1Department of Medicine, St. Johns Medical College and Hospital, St. Johns National Academy of Health Sciences, Bangalore, India.

The Journal of the Association of Physicians of India
|December 5, 2008
PubMed
Summary
This summary is machine-generated.

Melioidosis, an emerging infectious disease in India, can present with diverse symptoms. Early diagnosis of Burkholderia pseudomallei infection is crucial for effective treatment.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Melioidosis is an emerging infectious disease in India.
  • Acquisition occurs via percutaneous inoculation or contaminated water.
  • Risk factors include diabetes mellitus, renal failure, cirrhosis, and malignancy.

Observation:

  • A 42-year-old male from a non-endemic region presented with a two-month fever.
  • The patient exhibited sepsis, persistent pneumonia, hip joint pain, and hepatic/splenic abscesses.
  • Gram-negative bacilli, identified as Burkholderia pseudomallei, were cultured from joint and fluid aspirates.

Findings:

  • The case highlights the protean manifestations of Melioidosis.
  • Burkholderia pseudomallei was confirmed as the causative agent.
  • Diagnosis involved joint aspiration and fluid culture.

Implications:

  • This case underscores the importance of considering Melioidosis in febrile illnesses, even in non-endemic areas.
  • Understanding the epidemiology and clinical features aids in early diagnosis.
  • Prompt laboratory identification and appropriate treatment are vital for patient outcomes.