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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
07:27

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis

Published on: February 24, 2023

Melioidosis

P Krishnan1, Sushmitha Fernandes, Jayanthi Savio

  • 1Department of Medicine, St. Johns Medical College and Hospital, St. Johns National Academy of Health Sciences, Bangalore, India.

The Journal of the Association of Physicians of India
|December 5, 2008
PubMed

Insights

Melioidosis, an emerging infectious disease in India, can present with diverse symptoms. Early diagnosis of Burkholderia pseudomallei infection is crucial for effective treatment.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Melioidosis is an emerging infectious disease in India.
  • Acquisition occurs via percutaneous inoculation or contaminated water.
  • Risk factors include diabetes mellitus, renal failure, cirrhosis, and malignancy.

Observation:

  • A 42-year-old male from a non-endemic region presented with a two-month fever.
  • The patient exhibited sepsis, persistent pneumonia, hip joint pain, and hepatic/splenic abscesses.
  • Gram-negative bacilli, identified as Burkholderia pseudomallei, were cultured from joint and fluid aspirates.

Findings:

  • The case highlights the protean manifestations of Melioidosis.
  • Burkholderia pseudomallei was confirmed as the causative agent.
  • Diagnosis involved joint aspiration and fluid culture.

Implications:

  • This case underscores the importance of considering Melioidosis in febrile illnesses, even in non-endemic areas.
  • Understanding the epidemiology and clinical features aids in early diagnosis.
  • Prompt laboratory identification and appropriate treatment are vital for patient outcomes.

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