Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Overview of Pulmonary Circulation

Overview of Pulmonary Circulation

The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...

Overview of Systemic and Pulmonary Circulation

Overview of Systemic and Pulmonary Circulation

The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...

Anatomy of the Circulatory System

Anatomy of the Circulatory System

The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.

Overview of Systemic Arteries

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.

Fetal Circulation

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

Cardiovascular System Abnormal Findings I: Inspection and Palpation

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of olfactory stimulation with L-menthol on sensations of discomfort on exertion in patients with chronic lung diseases.

Respiratory investigation·2026

Same author

Increased Orexin by High Concentration of Sevoflurane Enhances the Suprahyoid Muscle Activity Involves in Gasping-Like Respiration of Mice.

FASEB bioAdvances·2026

Same author

Orexin Receptor Antagonism Improves Sleep Quality and Mitigates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Same author

Significance of diffusing capacity of the lungs for carbon monoxide on chronic thromboembolic pulmonary hypertension.

Thorax·2026

Same author

Differential Transcriptomic Features of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis with and Without Extrapulmonary Lesions in an East Asian Population.

Biomedicines·2025

Same author

Long-term outcomes of Qing-Dai-induced pulmonary arterial hypertension.

ERJ open research·2025

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

Published on: February 11, 2017

[Normal and abnormal pulmonary circulation].

Koichiro Tatsumi¹

¹Department of Respirology, Graduate School of Medicine, Chiba University.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|December 5, 2008

Summary

Pulmonary hypertension involves structural changes in lung vasculature. Understanding normal lung vascular structure is key to studying and potentially reversing these remodeling processes.

Area of Science:

Pulmonary vascular remodeling
Cardiovascular research
Pathophysiology of lung diseases

Context:

Pulmonary hypertension (PH) is characterized by vascular structural changes.
While reversible components like vasoconstriction exist, structural remodeling is the basis of clinical PH.
The lung's unique vascular architecture is central to understanding PH.

Purpose:

To highlight the critical role of vascular remodeling in pulmonary hypertension.
To emphasize the importance of understanding normal pulmonary vascular structure for therapeutic development.
To identify key areas for research into mediators of cell injury and tissue remodeling in PH.

Summary:

Structural remodeling of the lung's vasculature is the defining feature of pulmonary hypertension (PH).

More Related Videos

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

Related Experiment Videos

Last Updated: Jun 27, 2026

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

Published on: February 11, 2017

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

Research into mediators of cell injury and tissue remodeling is crucial for understanding PH.

The specific cellular composition and regional differences within the pulmonary vascular bed influence remodeling patterns.

Impact:

Provides a foundational understanding of pulmonary hypertension pathophysiology.
Guides future research directions for targeted therapies.
Enhances knowledge of lung vascular adaptation and disease.