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Updated: Jun 27, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Medication administration through enteral feeding tubes.
1Pharmacy Practice, College of Pharmacy, Southwestern Oklahoma State University, c/o Norman Regional Health System, Pharmacy Services, 901 North Porter, Box 1308, Norman, OK 73070, USA. nancy.williams@swosu.edu
Administering medications via enteral feeding tubes requires careful selection of drug formulations and administration techniques to prevent complications like tube occlusion and ensure medication efficacy. Proper flushing and awareness of drug-formula interactions are crucial for safe and effective delivery.
Area of Science:
- Gastroenterology
- Clinical Pharmacy
- Nutrition Support
Background:
- Enteral nutrition is vital for patients unable to eat orally.
- Feeding tubes are commonly used for medication delivery in these patients.
- Concurrent administration of medications and enteral formulas presents unique challenges.
Purpose of the Study:
- To provide an overview of enteral feeding tubes.
- To discuss drug administration techniques and dosage form selection.
- To highlight drug-formula interactions and methods to prevent tube occlusion.
Main Methods:
- Review of literature on enteral feeding tubes and drug administration.
- Analysis of factors influencing drug delivery through feeding tubes.
- Identification of common drug-nutrient interactions and administration precautions.
Main Results:
- Liquid formulations are preferred but can cause adverse effects.
- Solid dosage forms require careful manipulation (crushing/opening).
- Specific drugs (phenytoin, warfarin, etc.) need special administration considerations.
Conclusions:
- Successful drug delivery depends on tube characteristics and appropriate drug/dosage form selection.
- Proper flushing techniques are essential to prevent tube occlusion.
- Avoiding direct addition of medications to formulas is critical.
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