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Related Concept Videos

Archival Research01:40

Archival Research

Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific primer.
Since the...
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...
The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Online reprint request: search, access, read, and update.

Garehatty Rudrappa Kanthraj1

  • 1Department of Dermatology, Venereology and Leprosy, Jagadguru Sri Shivarathreshwara University Medical College Hospital, Ramanuja Road, Mysore, Karnataka, India. kanthacad@yahoo.com

Indian Journal of Dermatology, Venereology and Leprology
|December 5, 2008
PubMed
Summary

Online reprint requests (ORR) offer a cost-effective way to obtain scientific literature. This method overcomes email decay and unavailable addresses by providing alternative contact strategies for essential research materials.

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Area of Science:

  • Information Science
  • Bibliometrics
  • Scholarly Communication

Background:

  • Online reprint requests (ORR) are standard for accessing scientific literature when direct access is unavailable.
  • ORR reduces costs and delivery times compared to traditional surface mail.
  • Limitations include message failure, email decay, and missing author email addresses.

Purpose of the Study:

  • To analyze practical solutions for overcoming barriers in the ORR process.
  • To ensure the continued exchange of scientific information despite technical challenges.
  • To provide a protocol for obtaining scientific literature when library access is limited.

Main Methods:

  • Investigating alternative strategies for ORR when initial attempts fail.
  • Prioritizing contact methods in a specific order: author's latest email, co-author's email, institutional email, or postal request.
  • Documenting the process for utilizing pooled literature in educational settings.

Main Results:

  • A tiered approach to reprint requests effectively addresses email decay and missing contact information.
  • The protocol facilitates obtaining necessary scientific literature even with limited resources.
  • Successful implementation allows for the use of shared literature in teaching and research.

Conclusions:

  • The proposed ORR protocol enhances scientific information exchange by providing robust solutions to common technical barriers.
  • This systematic approach ensures researchers can access vital literature, supporting continuous learning and research.
  • Utilizing pooled literature resources supports educational initiatives and professional development in scientific fields.