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Updated: Jun 27, 2026

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
Published on: August 14, 2015
Subthalamic role on the generation of spikes in temporal epilepsy
Elena Urrestarazu1, Jorge Iriarte, Manuel Alegre
1Department of Neurology and Neurosurgery, Clínica Universitaria and Medical School, and Neurosciences Division, CIMA University of Navarra, Pamplona, Spain.
Summary:
We report the electrophysiological findings in an unusual patient with temporal lobe epilepsy and subthalamic stimulators implanted to treat Parkinson's disease. Temporal and frontotemporal spikes were observed in the EEG. Temporal spikes spread to the STN in a 40% of cases, involving simultaneously all contacts. Frontotemporal spikes showed more frequent STN propagation (70%), shorter delays, and progressive spread from ventral to dorsal contacts than temporal spikes. These results suggest that a direct fronto-subthalamic pathway might account for the fast propagation of the frontotemporal spikes to the ventral STN.
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