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Updated: Jun 27, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Pharmacotherapy for meconium aspiration.

A Asad¹, R Bhat

¹Division of Neonatology, Department of Pediatrics, University of Illinois at Medical Center, Chicago, IL 60612, USA.

Journal of Perinatology : Official Journal of the California Perinatal Association

|December 17, 2008

Summary

This review covers pharmacological treatments for meconium aspiration syndrome in infants, including ventilatory support, surfactant, and inhaled nitric oxide (INO). It also discusses emerging therapies, some lacking randomized controlled trials.

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Last Updated: Jun 27, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

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Published on: August 4, 2021

Area of Science:

Neonatalogy
Pediatric Pharmacology

Background:

Meconium aspiration syndrome (MAS) is a significant cause of respiratory distress in newborns.
Persistent pulmonary hypertension (PPHN) often complicates MAS, requiring intensive management.

Purpose of the Study:

To review current and emerging pharmacological treatment options for MAS with or without PPHN in infants.
To provide an overview of novel therapeutic strategies for MAS.

Main Methods:

Comprehensive literature review of pharmacological interventions for MAS.
Discussion of established treatments such as ventilatory support, surfactant therapy, and inhaled nitric oxide (INO).

Main Results:

Established treatments like ventilatory support, surfactant, and INO are detailed.
Emerging pharmacological treatments including sedatives, muscle relaxants, alkali infusion, antibiotics, and vasodilators are presented.

Conclusions:

Current treatment strategies for MAS are evolving.
Many newer pharmacological treatments require further evaluation through randomized controlled trials to establish efficacy and safety.