Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery
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Updated: Jun 27, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
Published on: December 23, 2016
Ahn Na Koo1, Hong Jae Lee, Sung Eun Kim
1Nanomaterials Application Division, Korea Institute of Ceramic Engineering and Technology, Seoul, 153-801, Korea.
Abstract:
We report biocompatible, cell-permeable core-shell-corona polymer micelles bearing glutathione-cleavable shell cross-links, which allow the facilitated release of entrapped anticancer drugs at cytoplasm in response to an intracellular glutathione level.
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