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Updated: Jun 27, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
Published on: December 14, 2011
Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle
James P Morton1, Kathryn Holloway, Paul Woods
1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, 15-21 Webster Street, Liverpool L3 2ET, UK. j.p.morton@ljmu.ac.uk
Abstract:
This study investigates the effects of short-term endurance training on heat shock protein (HSP) adaptations of male and female human skeletal muscle. The data demonstrate that females did not respond to continuous or interval training in terms of increasing HSP content of the vastus lateralis muscle. In contrast, males displayed HSP adaptations to both training interventions. These data provide a platform for future human studies to examine a potential gender-specific stress response to exercise.
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