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Published on: August 15, 2022
Successful kidney transplantation from donation after cardiac death using a load-distributing-band chest compression
Junya Morozumi1, Etsuo Sakurai, Naoto Matsuno
1Emergency and Critical Care Medicine, Tokyo Medical University Hachioji Medical Center, Japan. junya99@tokyo-med.ac.jp
Insights
Donation after cardiac death (DCD) kidney transplantation is crucial. Mechanical chest compression devices can maintain renal blood flow during long warm ischemic times (WIT), improving transplant success.
Area of Science:
- Nephrology
- Transplant Surgery
- Cardiopulmonary Resuscitation
Background:
- Donation after cardiac death (DCD) is a growing source for vital organs in transplantation.
- Optimizing kidney procurement from DCD donors is critical for successful deceased renal transplantation in Japan.
- Minimizing warm ischemic time (WIT) or maintaining renal blood flow during WIT is essential for DCD kidney viability.
Observation:
- A case of successful kidney transplantation from a DCD donor is reported.
- A non-invasive load-distributing-band chest compression device (AutoPulse) was used to maintain aortic pressure.
- This device was employed during a prolonged WIT to preserve renal blood flow.
Findings:
- The use of a mechanical chest compression device successfully maintained renal blood flow during a long WIT in a DCD donor.
- This intervention facilitated a successful kidney transplantation.
Implications:
- Mechanical CPR devices may serve as a bridge to deceased organ donation, particularly in DCD scenarios.
- This approach could enhance the utilization of DCD organs for transplantation.
- Further research into mechanical CPR devices for DCD organ preservation is warranted.
Abstract:
Donation after cardiac death (DCD) is increasing in importance as a potential source of vital organs for clinical transplantation. In Japan, the method of kidney procurement from DCD is one of the critical factors in successful deceased renal transplantation. The efforts to shorten the warm ischemic time (WIT), which is defined as the time from cardiac arrest to initiation of cooling in situ, or maintaining adequate renal blood flow during WIT by consistent chest compression are essential. We experienced one case of successful kidney transplantation using a non-invasive load-distributing-band chest compression device using AutoPulse (ZOLL Circulation, Sunnyvale, California), which is designed for use as an adjunct to cardiopulmonary resuscitation (CPR) to maintain adequate aortic pressure. This is the first report of our experiences of successful kidney transplantation from DCD using a load-distributing-band chest compression device for maintaining renal blood flow during long WIT. We can speculate that this mechanical CPR device can become a bridge to deceased organ transplantation.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

