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Updated: Jun 27, 2026

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy
Published on: March 13, 2014
Plasma fatty acids metabolic profiling analysis of coronary heart disease based on GC-MS and pattern recognition
Xintian Zheng1, Jie Shen, Qiang Liu
1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Abstract:
A simple approach for comprehensive profiling of fatty acids in human plasma based on gas chromatography-mass spectrometry (GC-MS) was described and validated. With this method, plasma fatty acid metabolic profiles of 23 coronary heart disease (CHD) patients and 25 healthy subjects were determined. Pattern recognition technology was used to establishing differences in the metabolic profiles of these two groups. Furthermore, CHD patients with two different patterns in Traditional Chinese Medicine clinical practices could be classified by the corresponding metabolic profiles, and several potential biomarkers were discussed.
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