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Updated: Jun 27, 2026

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
Published on: April 20, 2016
MicroRNAs and the skin: tiny players in the body's largest organ
Michael Sand1, Thilo Gambichler, Daniel Sand
1Department of Dermatology, Ruhr-University Bochum, Gudrunstr. 56, 44791 Bochum, Germany. michael.sand@ruhr-uni-bochum.de
Abstract:
MicroRNAs (miRNAs) are very small endogenous RNA molecules about 22-25 nucleotides in length, capable of post-transcriptional gene regulation. miRNAs bind to their target messenger RNAs (mRNAs), leading to cleavage or suppression of target mRNA translation based on the degree of complementarity. miRNAs have recently been shown to play pivotal roles in diverse developmental and cellular processes and linked to a variety of skin diseases and cancers. Disruption of miRNA metabolism is also involved in wound healing and inflammatory skin conditions. Here, we review the role of miRNAs in cutaneous biology.
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