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Constitutively active GPR6 is located in the intracellular compartments

Shalini Padmanabhan1, Amanda G Myers, Balakrishna M Prasad

  • 1Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA.

FEBS Letters
|December 9, 2008
PubMed
Summary

G protein-coupled receptor 6 (GPR6) is mainly found inside cells, not on the surface. This intracellular GPR6 maintains its signaling activity, suggesting it functions from within cellular compartments.

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