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Related Concept Videos

What are Lipids?01:38

What are Lipids?

Overview
Biosynthesis of Lipids01:29

Biosynthesis of Lipids

Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis pathway, which...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipid Digestion01:06

Lipid Digestion

Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.

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Related Experiment Video

Updated: Jun 27, 2026

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Published on: July 14, 2022

How to study lipidomes.

Tuulikki Seppänen-Laakso1, Matej Oresic

  • 1VTT Technical Research Centre of Finland, Espoo, Finland.

Journal of Molecular Endocrinology
|December 9, 2008
PubMed
Summary
This summary is machine-generated.

Modern lipidomics offers a comprehensive view of cellular lipids, enabling new discoveries in physiology. These advanced techniques combine mass spectrometry and bioinformatics for detailed lipid analysis.

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Last Updated: Jun 27, 2026

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Published on: July 14, 2022

Shotgun Lipidomics of Rodent Tissues
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Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids
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Published on: May 15, 2019

Area of Science:

  • Biochemistry
  • Cell Biology
  • Physiology

Background:

  • The lipidome, encompassing all lipids in a biological system, is crucial for cellular functions.
  • Understanding the complete lipidome provides insights into organismal physiology.

Purpose of the Study:

  • To highlight the potential of modern lipidomics platforms for comprehensive lipidome analysis.
  • To underscore the application of lipidomics in both phenotyping and hypothesis-driven research.

Main Methods:

  • Utilizes advanced mass spectrometry technology.
  • Integrates bioinformatics methods with traditional sample preparation and lipid extraction techniques.

Main Results:

  • Enables obtaining a complete snapshot of the cellular/organismal lipidome for the first time.
  • Reveals numerous potential discoveries in lipid-related cellular and organismal physiology.

Conclusions:

  • Lipidomics platforms are transformative tools for exploring lipid biology.
  • These approaches facilitate the elucidation of specific pathways and gene functions.