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Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
Helicobacter pylori in solid-organ transplant recipient
Yoshihide Ueda1, Tsutomu Chiba
1Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto, Japan. yueda@kuhp.kyoto-u.ac.jp
Current Opinion in Organ Transplantation
|December 9, 2008
Summary
Helicobacter pylori (H. pylori) infection is common in organ transplant recipients, similar to the general population. Treatment is recommended to prevent peptic ulcers and MALT lymphoma post-transplant.
Area of Science:
- Gastroenterology
- Transplant Medicine
- Infectious Diseases
Background:
- Helicobacter pylori (H. pylori) infection is a known cause of upper gastrointestinal diseases.
- Individual variability exists in disease outcomes following H. pylori infection.
Purpose of the Study:
- To review and summarize the prevalence of H. pylori infection in organ transplant recipients.
- To examine the outcomes of H. pylori infection, including peptic ulcer and MALT lymphoma, after transplantation.
Main Methods:
- Literature review of published reports on H. pylori infection in organ transplant recipients.
- Summary of findings regarding prevalence and disease outcomes.
Main Results:
- H. pylori infection prevalence in solid-organ transplant recipients is comparable to non-transplant controls, potentially decreasing post-transplant.
- H. pylori infection is linked to peptic ulcer disease and MALT lymphoma post-transplantation, without increased incidence under immunosuppression.
- The association between H. pylori and de-novo gastric cancer post-transplantation requires further investigation.
Conclusions:
- Optimal management of H. pylori infection in solid-organ transplant recipients remains undetermined.
- H. pylori eradication is advised for positive recipients to prevent gastrointestinal diseases.
- Future studies should assess the efficacy of pre-transplant H. pylori eradication therapy.
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