Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Protein Complexes with Interchangeable Parts

Protein Complexes with Interchangeable Parts

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...

Protein Complexes with Interchangeable Parts

Protein Complexes with Interchangeable Parts

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...

Ladder Diagrams: Complexation Equilibria

Ladder Diagrams: Complexation Equilibria

Ladder diagrams are useful for evaluating equilibria involving metal-ligand complexes. The vertical scale of the ladder diagram represents the concentration of unreacted or free ligand, pL. The horizontal lines on the scale depict the log of stepwise formation constants for metal-ligand complexes and indicate the dominant species in all the regions.
The formation constant, K1, for the formation of Cd(NH3)2+ complex from cadmium and ammonia is 3.55 × 102. Log K1 (i.e. pNH3) is 2.55, and...

Design Example: Distributing Reinforcements in Concrete Sections

Design Example: Distributing Reinforcements in Concrete Sections

The topic explores the practical aspects of adjusting steel reinforcements within a concrete beam section to meet specific design requirements. When designing a reinforced concrete beam, it is essential to distribute the steel reinforcements properly to ensure structural integrity and efficiency. The example provided details a scenario where a beam requires a total steel cross-section of 4 square inches. The engineer identifies that the available steel bars have a nominal diameter of 1.693...

Three Force Member

Three Force Member

A rigid body subjected to three forces acting at three points is known as a three-force member. These forces must have concurrent lines of action, except for parallel forces, where the lines of action are parallel.
For example, consider a dumpster connected to a pin support at point A and a pin attached to a hydraulic cylinder at point B.

Space Trusses

Space Trusses

A space truss is a three-dimensional counterpart of a planar truss. These structures consist of members connected at their ends, often utilizing ball-and-socket joints to create a stable and versatile framework. The space truss is widely used in various construction projects due to its adaptability and capacity to withstand complex loads.
At the core of a space truss lies the fundamental unit known as the tetrahedron. This structure is composed of six members that form a three-dimensional shape...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection.

The New England journal of medicine·2018

Same author

Direct Observation of Plasmon-Induced Interfacial Charge Separation in Metal/Semiconductor Hybrid Nanostructures by Measuring Surface Potentials.

Nano letters·2017

Same author

The Role of Repulsion in Colloidal Crystal Engineering with DNA.

Journal of the American Chemical Society·2017

Same author

Connecting Together Nanocenters around the World.

ACS nano·2017

Same author

Large-Area Patterning of Metal Nanostructures by Dip-Pen Nanodisplacement Lithography for Optical Applications.

Small (Weinheim an der Bergstrasse, Germany)·2017

Same author

Upconversion Nanoprobes for the Ratiometric Luminescent Sensing of Nitric Oxide.

Journal of the American Chemical Society·2017

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

Triple-Decker Complexes Formed via the Weak Link Approach.

You-Moon Jeon¹, Jungseok Heo, Aaron M Brown

¹Department of Chemistry and the Institute for Nanotechnology, 2145 Sheridan Road, Evanston, Illinois 60208-3113.

Organometallics

|December 9, 2008

Summary

Researchers created switchable triple-decker complexes (TDCs) using a weak link method. These TDCs can be reversibly opened and closed to expose inner layers, offering tunable properties for advanced applications.

More Related Videos

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

Related Experiment Videos

Last Updated: Jun 27, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

Area of Science:

* Inorganic Chemistry
* Materials Science

Background:

* Triple-decker complexes (TDCs) are supramolecular structures with potential applications in catalysis and materials science.
* Existing methods for synthesizing and manipulating TDCs often lack reversibility and precise control over structural features.

Purpose of the Study:

* To develop a novel synthetic strategy for preparing semi-open and condensed triple-decker complexes (TDCs).
* To demonstrate the reversible chemical opening and closing of TDCs to expose the interior layer.
* To investigate the tunability of TDC layers through the selection of hemilabile ligands.

Main Methods:

* Employed a weak link approach for TDC synthesis.
* Utilized a halide-induced ligand rearrangement process.
* Performed small-molecule and elemental anion ligand substitution reactions for chemical switching.

Main Results:

* Successfully synthesized and fully characterized semi-open and condensed TDCs.
* Demonstrated reversible chemical switching of TDCs, exposing the interior layer.
* Showcased the ability to tailor TDC layers by selecting specific hemilabile ligand starting materials.

Conclusions:

* The weak link approach and halide-induced rearrangement provide a robust method for TDC synthesis.
* Reversible chemical opening and closing of TDCs is achievable, enabling dynamic structural control.
* Tailorable TDCs offer promising avenues for developing responsive materials and catalysts.