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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Jun 27, 2026

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Basal cell carcinoma does metastasize.

Doruk Ozgediz¹, E B Smith, Jie Zheng

¹Department of Surgery, University of California San Francisco, VA Medical Center San Francisco, California, USA.

Dermatology Online Journal

|December 9, 2008

Summary

This summary is machine-generated.

Basal cell carcinoma (BCC) rarely spreads. This case shows a neglected BCC metastasizing to lymph nodes, successfully treated with surgery and radiation, with no recurrence after 24 months.

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Area of Science:

Dermatology
Oncology

Background:

Basal cell carcinoma (BCC) is the most common skin cancer, characterized by its low metastatic potential.
Metastasis from BCC is rare, typically associated with neglected or advanced primary tumors.

Observation:

A 52-year-old male presented with a left chest BCC that grew and ulcerated over six years.
The tumor subsequently metastasized to the lymph nodes in the left axilla.

Findings:

The patient underwent wide excision of the primary tumor and dissection of the affected lymph nodes.
Adjuvant local radiation therapy was administered to the axilla.

Implications:

Aggressive management including surgery and radiation can achieve disease control in rare metastatic BCC cases.
Early detection and treatment are crucial to prevent the progression and metastasis of basal cell carcinoma.