Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Preparation of Diols and Pinacol Rearrangement01:57

Preparation of Diols and Pinacol Rearrangement

Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subcutaneous nodules on the elbows of a teenager.

JAAD case reports·2026
Same author

Prompt recurrence of granuloma annulare upon Janus kinase inhibitor discontinuation.

JAAD case reports·2026
Same author

Discoid Lupus Erythematosus Successfully Treated With Anifrolumab.

Cureus·2026
Same author

Acute generalized exanthematous pustulosis sine pustules: A case report.

JAAD case reports·2026
Same author

Multinucleate cell angiohistiocytoma.

JAAD case reports·2025
Same author

Porokeratosis ptychotropica mimicking a herpes simplex virus infection.

JAAD case reports·2025
Same journal

Pellagra associated with iron deficiency.

Dermatology online journal·2026
Same journal

Demodicosis: A frequently underrecognized cause of recalcitrant ear pruritus.

Dermatology online journal·2026
Same journal

Association of alopecia areata with COVID-19 vaccination: A vaccine adverse events reporting system analysis.

Dermatology online journal·2026
Same journal

Gender based price differences in 5% minoxidil foam: The impact of generic alternatives and bulk packaging.

Dermatology online journal·2026
Same journal

Retrospective analysis of filler complications reported in the manufacturer and user facility device experience database from 2015 to 2025.

Dermatology online journal·2026
Same journal

Characterizing barriers to care in patients with hidradenitis suppurativa.

Dermatology online journal·2026
See all related articles

Related Experiment Video

Updated: Jun 27, 2026

Quantification of Hypopigmentation Activity In Vitro
06:08

Quantification of Hypopigmentation Activity In Vitro

Published on: March 6, 2019

Camouflaging vitiligo with dihydroxyacetone.

Sylvia Hsu

    Dermatology Online Journal
    |December 9, 2008
    PubMed
    Summary
    This summary is machine-generated.

    Dihydroxyacetone (DHA), a key ingredient in sunless tanners, offers a cosmetic solution for camouflaging vitiligo patches. This finding suggests a novel, accessible approach for improving the appearance of affected skin.

    More Related Videos

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    Related Experiment Videos

    Last Updated: Jun 27, 2026

    Quantification of Hypopigmentation Activity In Vitro
    06:08

    Quantification of Hypopigmentation Activity In Vitro

    Published on: March 6, 2019

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    Area of Science:

    • Dermatology
    • Cosmetic Science

    Background:

    • Vitiligo is a condition causing skin depigmentation.
    • Current treatments for vitiligo can be invasive or have limited efficacy.
    • Cosmetic camouflage is a sought-after option for patients.

    Observation:

    • Dihydroxyacetone (DHA) is the active component in sunless tanning products.
    • DHA reacts with skin proteins to create a tanned appearance.

    Findings:

    • Dihydroxyacetone demonstrated cosmetically acceptable camouflage for vitiligo.
    • The effect provides a temporary, non-invasive method to reduce the contrast of depigmented skin.

    Implications:

    • DHA offers a readily available and affordable option for vitiligo camouflage.
    • This approach may improve patient self-esteem and quality of life.
    • Further research could explore optimal DHA application techniques for vitiligo.