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Steroid-responsive facial eruption with cornoid lamellae--a possible new entity
Hien Tran1, Nicole M Bossenbroek, Karla Rosenman
1Department of Dermatology, New York University, USA.
Dermatology Online Journal
|December 9, 2008
Summary
Cornoid lamellation, a feature seen in porokeratosis, can appear in other skin conditions. This case highlights an inflammatory presentation not typical of porokeratosis, responding to topical steroids.
Area of Science:
- Dermatopathology
- Histopathology
Background:
- Cornoid lamellation is a histopathologic feature frequently associated with porokeratosis.
- However, this finding is not exclusive to porokeratosis and can be observed in various other dermatologic conditions.
Observation:
- This report details a unique case where lesions presented with both clinical and histopathological inflammatory features.
- The observed cornoid lamellae did not align with the typical presentation of porokeratosis.
Findings:
- Cornoid lamellation represents a reaction pattern of disordered epidermal cornification, not specific to a single disease process.
- The case demonstrated an inflammatory presentation of cornoid lamellation, distinct from classic porokeratosis.
Implications:
- The findings suggest that cornoid lamellation can manifest in inflammatory dermatoses, broadening its differential diagnosis.
- The patient's positive response to topical glucocorticoids indicates a potential therapeutic avenue for such inflammatory presentations.
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