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Minimal Erythema Dose (MED) Testing
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Erythema elevatum diutinum.

Rachel Farley-Loftus1, Chicky Dadlani, Nadia Wang

  • 1Department of Dermatology, New York University, USA.

Dermatology Online Journal
|December 9, 2008
PubMed
Summary
This summary is machine-generated.

Erythema elevatum diutinum is a rare vasculitis presenting as skin plaques. This case highlights its varied presentation and association with other conditions.

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Erythema elevatum diutinum (EED) is a rare, chronic leukocytoclastic vasculitis.
  • It presents as persistent, symmetrical papules, plaques, or nodules, typically on extensor surfaces.
  • EED is associated with various systemic conditions, including infections, autoimmune disorders, and malignancies.

Observation:

  • A 64-year-old woman presented with a year-and-a-half history of an enlarging, red-brown, firm plaque on her left thigh.
  • She also had multiple scattered, indurated, hyperpigmented patches on her lower extremities.
  • Histopathology of the largest plaque confirmed EED.

Findings:

  • Histopathological examination confirmed erythema elevatum diutinum.
  • This diagnosis indicates a form of leukocytoclastic vasculitis.
  • The condition can be linked to diverse underlying diseases.

Implications:

  • This case underscores the importance of considering EED in patients with persistent skin lesions.
  • Recognition of associated systemic conditions is crucial for comprehensive patient management.
  • While dapsone is the primary treatment, alternative therapies may be necessary.