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Yellow nail syndrome.

Sarina B Elmariah¹, Ravi R Ubriani, Olympia Kovich

¹Department of Dermatology, New York University, USA.

Dermatology Online Journal

|December 9, 2008

Summary

This summary is machine-generated.

Yellow Nail Syndrome (YNS) is a rare disorder causing nail changes, lymphedema, and respiratory issues. While its cause is unknown, spontaneous remission occurs in about 30% of patients.

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Area of Science:

Dermatology
Internal Medicine
Genetics

Background:

Yellow Nail Syndrome (YNS) is a rare disorder.
It is characterized by a triad of yellow dystrophic nails, lymphedema, and respiratory abnormalities.
However, it often manifests with only two of the three classic features.

Observation:

A 70-year-old man presented with a three-year history of thickened, slow-growing, yellow-to-green discolored fingernails and toenails.
He also had a concurrent history of chronic sinusitis with persistent productive cough.
His presentation was consistent with a diagnosis of YNS.

Findings:

The exact pathomechanism of YNS remains unknown.
It is hypothesized to involve lymphatic vasculature defects.
Spontaneous remission is observed in approximately 30% of affected individuals.

Implications:

YNS diagnosis requires careful evaluation of nail, lymphatic, and respiratory systems.
Limited treatment options necessitate further research into YNS pathogenesis.
Understanding lymphatic defects may offer future therapeutic targets for YNS.