Related Experiment Video
Updated: Jun 27, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
Fullerene derivatized s-triazine analogues as antimicrobial agents
Anish Kumar1, Shobhana Karuveettil Menon
1Department of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad 380009, Gujarat, India.
Abstract:
A series of novel fullerene derivatives bearing s-triazine moiety have been synthesized by adopting 1,3 dipolar cycloaddition reaction of C(60) and azomethine ylides generated from the corresponding Schiff bases of 2,4,6 trisubstituted s-triazine. All the compounds synthesized were characterized by elemental analysis, FT-IR, (1)H NMR, (13)C NMR and FAB-MS. The compounds were then screened for their antibacterial activity against both gram-positive (Staphylococcus aureus, Bacillus subtilis, Bacillus pumilis) and gram-negative (Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) bacteria by disc diffusion method. All the compounds were found to be active against these strains at very low concentration and were comparable to standard drug ciprofloxacin.
Related Concept Videos
Antifungal Agents
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Inhibitors of Bacterial DNA Synthesis
Anthelminthic Agents
Aromatic Hydrocarbon Cations: Structural Overview
Removing one hydrogen from the intervening CH2 group with both...
![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)
