[New-onset pulmonary tuberculosis in women]

A clinical pattern, a social portrait, and the efficiency of inpatient treatment were studied in females with new-onset pulmonary tuberculosis. Four hundred and twenty-eight cases of new-onset pulmonary tuberculosis in 18-85-year-old women admitted to a specialized hospital (95, 178, and 155 patients in 1990, 2001, and 2005, respectively). The pattern of clinical forms was found to become much worse under the present conditions of epidemiological ill-being. There was a rise in the incidence of the disseminated form from 10.5 to 23.9% with a drop in that of the focal form from 23.2 to 7.1%. Pulmonary tuberculosis is characterized with the great extent of involvement, the high rate of destructive changes, abundant bacterial excretion, the increase of drug resistance (DR), and worsening of its pattern due to polyresistance and multiple DR. The efficiency of inpatient treatment for pulmonary tuberculosis significantly decreased: bacterial excretion ceased in 52.4-52.9%, destructive changes were eliminated in 30.4-34.3%. Under the present conditions in combination with biomedical and social factors, the detected specific features of pulmonary tuberculosis affected the results of inpatient treatment.