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Peripheral Nervous System: Ganglia and Nerves

Peripheral Nervous System: Ganglia and Nerves

The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...

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Related Experiment Video

Updated: Jun 27, 2026

Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology

Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology

Published on: July 12, 2022

Peripheral nerve: what's new in basic science laboratories.

Jae W Song¹, Lynda J Yang, Stephen M Russell

¹Department of Neurosurgery, New York University School of Medicine, New York, NY 10016, USA.

Neurosurgery Clinics of North America

|December 10, 2008

Summary

This summary is machine-generated.

Basic science research in peripheral nerve regeneration is advancing clinical treatments for nerve defects. New studies explore nerve allotransplantation and electrical stimulation, alongside novel transgenic mice for enhanced investigation.

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Toluidine Blue Staining of Resin-Embedded Sections for Evaluation of Peripheral Nerve Morphology

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Published on: July 3, 2018

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Last Updated: Jun 27, 2026

Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology

Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology

Published on: July 12, 2022

Toluidine Blue Staining of Resin-Embedded Sections for Evaluation of Peripheral Nerve Morphology

Toluidine Blue Staining of Resin-Embedded Sections for Evaluation of Peripheral Nerve Morphology

Published on: July 3, 2018

Area of Science:

Neuroscience
Regenerative Medicine

Background:

Decades of basic science research have laid the foundation for clinical applications in peripheral nerve regeneration.
Peripheral nerve defects present significant challenges requiring innovative treatment strategies.

Purpose of the Study:

To review current clinical applications for peripheral nerve defects.
To highlight advancements in nerve regeneration research.

Main Methods:

Discussion of nerve allotransplantation as a clinical application.
Review of electrical stimulation techniques to promote nerve regeneration.
Introduction of Thy-1-XFP transgenic mice for research.

Main Results:

Nerve allotransplantation and electrical stimulation have progressed from laboratory investigation to clinical testing.
Thy-1-XFP transgenic mice offer new possibilities for studying peripheral nerve regeneration.

Conclusions:

Basic science discoveries are translating into viable clinical treatments for peripheral nerve injuries.
Advanced research models, like Thy-1-XFP mice, will accelerate future progress in nerve regeneration.