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Updated: Jun 27, 2026
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
Transcranial direct current stimulation in stroke recovery.
Gottfried Schlaug1, Vijay Renga, Dinesh Nair
1Neuroimaging and Stroke Recovery Laboratories, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA. gschlaug@bidmc.harvard.edu
Transcranial direct current stimulation (TDCS) offers a promising noninvasive approach to aid stroke recovery. This technique modulates brain plasticity, potentially improving outcomes for patients undergoing neurological rehabilitation.
Area of Science:
- Neuroscience
- Neurology
- Rehabilitation Medicine
Background:
- Transcranial direct current stimulation (TDCS) is an emerging noninvasive brain stimulation technique.
- TDCS is used to examine cortical function and treat neurological disorders.
- Understanding post-stroke neuroplasticity is key for developing new treatments.
Purpose of the Study:
- To review the role of TDCS in facilitating stroke recovery.
- To discuss different modes of TDCS application.
- To explore the potential neural mechanisms of TDCS in stroke rehabilitation.
Main Methods:
- Literature review of studies on TDCS and stroke recovery.
- Analysis of adaptive and maladaptive neuroplasticity post-stroke.
- Examination of TDCS modulation of neural effects.
Main Results:
- TDCS shows potential as an experimental treatment for stroke recovery.
- Different TDCS modes may influence outcomes.
- Further research is needed to fully understand underlying neural mechanisms.
Conclusions:
- TDCS is a promising noninvasive brain stimulation technique for stroke recovery.
- Modulating neuroplasticity with TDCS offers new therapeutic avenues.
- Understanding TDCS mechanisms is crucial for optimizing its clinical application.
