Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 27, 2026

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

Three-dimensional sprayed active biological gels and cells for tissue engineering application.

S Facca1, P Gillet, J-F Stoltz

  • 1Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 595, Faculté de Médecine, Strasbourg, France.

Bio-Medical Materials and Engineering
|December 10, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Higher preoperative range of motion is predictive of good mid-term results in the surgical management of osteochondral lesions of the talus: a prospective multicentric study.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2022
Same author

Dermatological adverse effects of anti-glaucoma eye drops: a review.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Investigating the impact of remediation efforts on Hedistediversicolor in the Seine estuary using multiple levels of biological organization.

Marine environmental research·2021
Same author

[Knee pain in a child : watch out for the hip !]

Revue medicale de Liege·2021
Same author

[How I explore… a non-traumatic gonalgia].

Revue medicale de Liege·2021
Same author

[Osteosynthesis for proximal humeral fractures : plate or nail ? Results of a retrospective monocentric study].

Revue medicale de Liege·2020
Same journal

Experimental study on deantigenization and trabecular structure effects on bovine cancellous bone compression.

Bio-medical materials and engineering·2026
Same journal

Effects of dentin extract without demineralization on migration and angiogenic potential of human umbilical vein endothelial cells.

Bio-medical materials and engineering·2026
Same journal

Measurement of thermal expansion coefficient of melanin for photoacoustic technology.

Bio-medical materials and engineering·2026
Same journal

Development of chitosan-selenium nanoparticle modified brushite cement: A potential strategy for improved clinical performance in bone regeneration.

Bio-medical materials and engineering·2026
Same journal

Electrostatic layer-by-layer assembly for fabricating morphology-controlled hydroxyapatite/zirconia composite with enhanced osteogenic performance.

Bio-medical materials and engineering·2026
Same journal

The antitumor activity of bismuth lipophilic nanoparticles (BisBAL NPs) on human glioblastoma is higher than temozolomide.

Bio-medical materials and engineering·2026
See all related articles

Researchers developed a novel spraying technique to create complex 3D biomaterials for tissue engineering. This method precisely controls the distribution of cells and matrix components, enabling functional tissue reconstruction.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Biotechnology

Background:

  • Fabricating complex 3D structures for tissue regeneration requires precise control over component distribution.
  • Traditional methods often lack the ability to precisely arrange diverse elements like cells and biomolecules in a 3D matrix.

Purpose of the Study:

  • To develop an innovative spraying technique for constructing functionalized 3D biomaterials.
  • To enable controlled, layer-by-layer assembly of complex biological tissues.
  • To investigate the feasibility of using this method for tissue engineering applications.

Main Methods:

  • Utilizing an alternate spraying approach for alginate and calcium ions to form a gel matrix.
  • Incorporating active alginate gel with various cell types via spraying.

More Related Videos

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
09:23

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration

Published on: June 16, 2015

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
11:28

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

Related Experiment Videos

Last Updated: Jun 27, 2026

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
09:23

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration

Published on: June 16, 2015

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
11:28

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

  • Building layered active reservoirs above and below the cell-laden gel structure.
  • Monitoring the viability and activity of sprayed cells over time.

    • Main Results:

    • Demonstrated successful fabrication of alginate gels through sequential spraying.
    • Confirmed the ability to spray active gels containing viable cells.
    • Established a method for creating layered reservoirs for controlled release.
    • Showcased sustained cell activity within the sprayed 3D structure.
    • Validated the potential of the spraying technique for tissue engineering.

    Conclusions:

    • The proposed spraying method offers precise control over the spatial distribution of matrix components and cells in 3D biomaterials.
    • This technique is suitable for building functionalized scaffolds for tissue engineering applications.
    • The approach allows for the creation of complex, multi-layered structures with sustained biological activity.