[Effect of nitroglycerin and nicardipine on ICG excretion during halothane anesthesia]

We evaluated the effect of nitroglycerin and nicardipine on ICG excretion during halothane anesthesia in man. Induced hypotension with nitroglycerin during halothane anesthesia produced a significant prolongation in ICG excretion. No such significant prolongation occurred in the patients who received nicardipine. The results suggest that a reduction in hepatic blood flow during anesthesia may be much less in patients who receive halothane with nicardipine than in those who receive halothane with nitroglycerin.