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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...

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Related Experiment Video

Updated: Jun 27, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

[Ocular changes in preeclampsia].

D Mihu1, Carmen Mihaela Mihu, Simona Tălu

  • 1Clinica Obstetrică-Ginecologie "Dominic Stanca", B-Dul 21 Decembrie NR. 55-57, Cluj-Napoca. dan.mihu@yahoo.com

Oftalmologia (Bucharest, Romania : 1990)
|December 11, 2008
PubMed
Summary
This summary is machine-generated.

Pregnancy complications like pre-eclampsia cause significant eye changes, including retinal vascular alterations. Early detection and multidisciplinary care are crucial for managing these risks.

Related Experiment Videos

Last Updated: Jun 27, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Area of Science:

  • Ophthalmology
  • Obstetrics
  • Vascular Medicine

Background:

  • Pregnancy induces systemic changes affecting multiple organs, including the eyes.
  • Ocular manifestations in pre-eclampsia (PE) range from retinal arteriolar vasoconstriction (30-100% of cases) to rare exudative retinal detachment.
  • Cortical blindness due to occipital anomalies and Purtscher retinopathy from retinal arteriole embolism are severe visual complications.

Purpose of the Study:

  • To explore the role of ophthalmic arterial flow evaluation using eco Doppler in understanding pre-eclampsia pathophysiology.
  • To assess the diagnostic and prognostic value of ophthalmic Doppler in quantifying pre-eclampsia severity.
  • To investigate the persistent vascular changes post-partum.

Main Methods:

  • Ophthalmic arterial flow was evaluated using eco Doppler in pregnant women with pre-eclampsia.
  • Impedance (IP) values and median velocity in the ophthalmic artery were analyzed.
  • Orbital vessel impedance was assessed in severe pre-eclampsia cases.

Main Results:

  • Decreased ophthalmic artery impedance (IP) and increased median velocity suggest hyperperfusion and reduced vascular resistance in orbital vessels and CNS in PE.
  • Severe PE cases show increased orbital vessel impedance.
  • Vascular changes may persist for over 6 weeks postpartum, indicating residual arteriolar constriction.

Conclusions:

  • Ophthalmic arterial flow assessment via eco Doppler offers new insights into pre-eclampsia pathophysiology, diagnosis, and severity.
  • Persistent vascular changes highlight the long-term impact of pre-eclampsia on ocular circulation.
  • A multidisciplinary team approach is essential for optimal management and improved outcomes in pre-eclampsia.