Chronic retinal pigment epithelial detachments with unusual clinical, angiographic, and tomographic presentations

The authors report two cases of central serous chorioretinopathy of long duration where retinal pigment epithelial detachment presented with unusual clinical features and led to misdiagnosis of a cystic mass lesion in one patient. Fluorescein angiography showed atypical fluorescence patterns, which did not help to diagnose or explain the clinical appearance. Optical coherence tomography confirmed the diagnosis and explained the anatomic basis of the anomalous clinical and angiographic presentation by highlighting the atrophic changes in the retinal pigment epithelial lining of the pigment epithelial detachment in both cases.