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Related Concept Videos

Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Antiviral Nucleoside Inhibitors01:22

Antiviral Nucleoside Inhibitors

Antiviral Nucleoside InhibitorsAntiviral nucleoside inhibitors are structural analogs of natural nucleosides that interfere with viral DNA or RNA synthesis. These compounds selectively target viral polymerases due to their resemblance to host nucleosides, thereby disrupting viral genome replication.Mechanism of Acyclovir ActionAcyclovir is a guanosine analog with a three-carbon acyclic side chain. It selectively targets herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2),...
Viruses of Archaea01:29

Viruses of Archaea

Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
Retroviruses02:33

Retroviruses

Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...

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Related Experiment Video

Updated: Jun 27, 2026

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
12:22

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

The order Herpesvirales.

Andrew J Davison1, Richard Eberle, Bernhard Ehlers

  • 1MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow, UK. a.davison@mrcvu.gla.ac.uk

Archives of Virology
|December 11, 2008
PubMed
Summary
This summary is machine-generated.

The International Committee on Taxonomy of Viruses (ICTV) has updated herpesvirus taxonomy, creating the order Herpesvirales with three new families: Herpesviridae, Alloherpesviridae, and Malacoherpesviridae. This revision reflects new classifications for viruses across various animal species.

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Last Updated: Jun 27, 2026

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Published on: April 2, 2012

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08:26

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Published on: August 31, 2017

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
10:40

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Published on: December 21, 2019

Area of Science:

  • Virology
  • Taxonomy
  • Molecular Biology

Background:

  • The classification of herpesviruses has undergone significant revisions.
  • The International Committee on Taxonomy of Viruses (ICTV) is responsible for virus nomenclature and classification.

Purpose of the Study:

  • To detail the recent updates in herpesvirus taxonomy.
  • To introduce the new order Herpesvirales and its constituent families and genera.

Main Methods:

  • Review and implementation of the latest taxonomic proposals by the ICTV.
  • Analysis of viral genetic and biological characteristics for classification.

Main Results:

  • The former family Herpesviridae was split into three families: Herpesviridae, Alloherpesviridae, and Malacoherpesviridae, forming the new order Herpesvirales.
  • New genera (Proboscivirus, Macavirus, Percavirus, Ostreavirus) were established, and species were reclassified or newly defined.
  • Specific changes include the reallocation of fish and frog viruses to Alloherpesviridae and a bivalve virus to Malacoherpesviridae.

Conclusions:

  • The revised herpesvirus taxonomy provides a more accurate and comprehensive classification system.
  • These taxonomic changes facilitate a better understanding of herpesvirus evolution and diversity across different hosts.