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Related Concept Videos

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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Related Experiment Video

Updated: Jun 27, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Congenital anetoderma in a preterm infant.

E Mary Wain1, Jemima E Mellerio, Alistair Robson

  • 1St John's Institute of Dermatology, St Thomas' Hospital, London, United Kingdom. marywain@doctors.net.u

Pediatric Dermatology
|December 11, 2008
PubMed
Summary

This study reports the first case of widespread congenital anetoderma in an infant born prematurely at 24 weeks gestation. It explores potential causes for this rare neonatal skin condition.

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Published on: June 24, 2020

Area of Science:

  • Neonatology
  • Dermatology
  • Pediatrics

Background:

  • Anetoderma is a rare skin condition characterized by the loss of elastic tissue, leading to herniations of the skin.
  • Congenital anetoderma is exceptionally rare, with limited documented cases, often associated with prematurity.

Observation:

  • A case of widespread congenital anetoderma is presented in an infant born at 24 weeks of gestation.
  • The infant weighed 640 g at birth, indicating significant prematurity.

Findings:

  • This represents the first reported instance of extensive congenital anetoderma in such a premature infant.
  • The study aims to discuss potential etiological factors contributing to this severe presentation.

Implications:

  • This case highlights the spectrum of congenital anetoderma and its potential severity in extremely preterm infants.
  • Further research into the etiology of congenital anetoderma may inform future clinical management and understanding of neonatal skin fragility.